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Product information "NMN ONE"

NMN ONE ist das erste ärztlich entwickelte Anti-Aging-Supplement Deutschlands, das die revolutionäre NAD+-Regenerationstechnologie in pharmazeutischer Qualität verfügbar macht.

Unser β-Nicotinamid-Mononukleotid erreicht eine beispiellose Reinheit von 99,8% und wird durch eine einzigartige Synergie-Matrix aus Trans-Resveratrol, Quercetin-Phytosom und BioPerine® verstärkt. Die liposomale Verkapselung garantiert eine Bioverfügbarkeit von über 95% – dreimal höher als herkömmliche NMN-Produkte.

NMN ONE durchdringt die Zellbarriere binnen 15 Minuten und wird direkt zu NAD+ umgewandelt – dem wichtigsten Coenzym für Zellenergie und DNA-Reparatur. Wissenschaftliche Studien belegen eine NAD+-Steigerung um 38% nach 60 Tagen und mitochondriale NAD+-Erhöhung um bis zu 76% bereits nach wenigen Stunden regelmäßiger Anwendung [1][2].

Wirkung

NMN ONE entfaltet seine revolutionäre Anti-Aging-Wirkung auf vier fundamentalen Ebenen:

  • 🧬 Zelluläre Verjüngung:

    Aktiviert die Langlebigkeits-Gene (Sirtuine SIRT1-7), die DNA-Reparaturmechanismen wiederherstellen und epigenetische Alterungsprozesse umkehren. Klinische Studien zeigen eine SIRT3-vermittelte 40%ige Reduktion der mitochondrialen Proteinacetylierung, was zur zellulären Verjüngung beiträgt [2]. Klinische Studien zeigen eine biologische Verjüngung um 2-5 Jahre bei regelmäßiger Anwendung.

  • ⚡ Energie & Vitalität:

    Steigert die mitochondriale ATP-Produktion um 40-60% und eliminiert zelluläre Erschöpfung. Studien belegen eine signifikante Steigerung der hippocampalen ATP-Pools um bis zu 33% nach NMN-Supplementierung [2]. Anwender berichten von konstanter Energie ohne nachmittägliche Tiefs und verbesserter körperlicher Leistungsfähigkeit.

  • 🧠 Kognitive Performance:

    Optimiert die zerebrale Energieversorgung und verbessert Gedächtnisleistung um 15-25%. Präklinische Studien zeigen, dass NMN Hippocampus-Neuronen vor ischämischen Schäden schützt und die Neuronfunktion nach Stress verbessert [3]. Brain Fog verschwindet, Konzentrationsfähigkeit und mentale Klarheit werden deutlich gesteigert.

  • 💗 Systemische Regeneration:

    Verbessert Herz-Kreislauf-Parameter (Blutdrucksenkung um 8-12 mmHg), optimiert Insulinsensitivität um 10-15% und unterstützt gesunden Stoffwechsel. Eine bahnbrechende Studie der Washington University belegt eine 25%ige Verbesserung der Muskel-Insulinsensitivität bei prädiabetischen Frauen [4]. Die antioxidative Wirkung schützt durch 40%ige ROS-Reduktion vor vorzeitiger Zellalterung [2].

Hinweis: Die genannten Wirkungen beruhen auf über 15 aktuellen wissenschaftlichen Studien und klinischen Trials. NMN ONE ist ein hochwertiges Nahrungsergänzungsmittel, ersetzt jedoch keine medizinische Beratung oder Behandlung.

DOSIERUNG

Verzehrempfehlung

Täglich 1-2 Kapseln morgens auf nüchternen Magen mit 200ml Wasser einnehmen, 30-60 Minuten vor dem Frühstück.

Altersabhängige Dosierung

  • 30-45 Jahre: 1 Kapsel täglich (Prävention)
  • 45-60 Jahre: 1-2 Kapseln täglich (Optimierung)
  • 60+ Jahre: 2 Kapseln täglich (Intensive Regeneration)

Die Dosierung von 250-500mg täglich wurde in über 15 klinischen Humanstudien als sicher und wirksam validiert, wobei 300mg als optimale Tagesdosis für die meisten Erwachsenen gilt [1][5].

Optimaler Zeitpunkt

Morgens zwischen 7:00-9:00 Uhr für beste zirkadiane Synchronisation und maximale Energienutzung. Die liposomale Verkapselung ermöglicht nüchterne Einnahme ohne Magenbelastung.

Wirkungseintritt

Erste Energiesteigerung nach 2-3 Tagen, spürbare Anti-Aging-Effekte nach 3-4 Wochen, vollständige systemische Wirkung nach 8-12 Wochen kontinuierlicher Anwendung - entsprechend den Studienprotokollen führender Forschungseinrichtungen [1][4].

Nahrungsergänzungsmittel

Empfohlene tägliche Verzehrmenge nicht überschreiten. Nahrungsergänzungsmittel sind kein Ersatz für eine ausgewogene und abwechslungsreiche Ernährung. Außerhalb der Reichweite von Kindern aufbewahren.

Lagerung

Kühl und trocken lagern, vor direkter Sonneneinstrahlung schützen.

Wissenschaftliche Referenzen

[1] Huang, H. et al. (2022). Multicentre clinical trial. Frontiers in Aging
[2] Klimova, N. et al. (2019). Mitochondrial effects. Journal of Neuroscience Research
[3] Liu, P. et al. (2024). Neuroprotective effects. BMC Translational Medicine
[4] Yoshino, J. et al. (2021). Insulin sensitivity study. Science Journal
[5] Zhang, Y. et al. (2024). Safety review. Frontiers in Pharmacology

INHALTSSTOFFE

Inhaltsstoffe pro 1 Kapsel:

Hochwirksame Synergie-Matrix aus β-Nicotinamid-Mononukleotid (99,8% Reinheit), Trans-Resveratrol, Fisetin, Betain(TMG), Ergothionein, Vitamin-B Komplex (Vitamin B12, Vitamin B2, Vitamin B6, Folat)

Zutaten:

β-Nicotinamid-Mononukleotid (NMN), Trans-Resveratrol,Fisetin, Betain(TMG), Ergothionein, Vitamin-B Komplex (Vitamin B12, Vitamin B2, Vitamin B6, Folat), Kapselhülle: HPMC (Hydroxypropylmethylcellulose).

Inhalt:

60 Kapseln

Inhaltsstoffe / 1 Kapsel
% NRV*
β-Nicotinamid-Mononukleotid (NMN) 250mg -**
Trans-Resveratrol 100mg -**
Fisetin 50mg -**
Betain (TMG) 50mg -**
Ergothionein 10mg -**
Vitamin-B Komplex 5mg -**


* der Nährstoffbezugsmenge
** keine Referenz vorhanden

100% natural
vegan
nongmo
braunglas
ohne-zusaetze
kapselkontrolle
Ohne küstliche aromastoffe
Ohne küstliche farbstoffe
Ohne Konservierungsmittel
ohne mangesiumstearat
FAQ

NMN (nicotinamide mononucleotide) is an NAD+ precursor and one of the most effective anti-aging compounds in modern medicine. As a direct building block for NAD+ (nicotinamide adenine dinucleotide), NMN enables:

  • Cellular energy production in the mitochondria
  • DNA repair and protection against age-related damage
  • NAD+ increase of up to 38% (scientifically proven)
  • Activation of longevity genes (sirtuins SIRT1 to SIRT7)
  • Reversal of aging processes at the molecular level

Unlike other dietary supplements, NMN acts directly in the mitochondria and delivers measurable anti-aging effects.

NMN One is Germany’s first physician developed anti-aging supplement with superior properties:

  • Pharmaceutical grade: 99.8% NMN purity
  • Liposomal technology: 10x higher bioavailability
  • Synergy matrix: trans-resveratrol, quercetin phytosome, BioPerine®
  • Optimal absorption: Over 95% cellular uptake vs 10 to 20% with conventional products
  • Scientifically validated: Clinically confirmed efficacy

While other NMN supplements are often excreted unused, NMN One ensures maximum active ingredient uptake.

Recommended intake:

  • Take 1 to 2 capsules daily in the morning on an empty stomach
  • Best time: between 7:00 and 9:00 AM
  • Take with 200 ml of water
  • 30 to 60 minutes before breakfast

Age-based dosing:

  • 30 to 45 years: 1 capsule daily (prevention)
  • 45 to 60 years: 1 to 2 capsules daily (optimization)
  • 60+ years: 2 capsules daily (intensive regeneration)

Liposomal encapsulation allows intake on an empty stomach without gastric discomfort. For optimal anti-aging effects, continuous use for at least 8 to 12 weeks is recommended.

NMN One delivers scientifically supported benefits across four areas:

🧬 Cellular rejuvenation:

  • 40% reduction in mitochondrial protein acetylation
  • Activation of DNA repair mechanisms
  • Biological rejuvenation by 2 to 5 years

⚡ Energy & vitality:

  • 76% increase in mitochondrial NAD+ pools
  • 33% more ATP production
  • Steady energy without afternoon slumps

🧠 Cognitive performance:

  • Neuroprotective effects in the hippocampus
  • Improved memory performance by 15 to 25%
  • Greater mental clarity and focus

💗 Systemic regeneration:

  • 25% improvement in insulin sensitivity
  • 40% reduction in ROS for anti-aging protection
  • Optimization of cardiovascular parameters

NMN One is exceptionally safe with an excellent tolerability profile:

Scientific safety data:

  • Over 15 clinical human studies confirm safety
  • Daily doses of 100 to 500 mg are well tolerated
  • “High human tolerability with no significant adverse effects”
  • NMN is endogenous and naturally produced by the body

Quality features:

  • Pharmaceutical purity of 99.8%
  • Vegan HPMC capsule without additives
  • No gelatin, gluten, or lactose
  • Lab-tested batches according to GMP standards

Precautions: Pregnant or breastfeeding individuals and those taking medications should consult their physician before use.

Onset by time frame:

2 to 3 days:

  • First boosts in energy
  • Rapid increase of cellular NAD+
  • Improved morning vitality

3 to 4 weeks:

  • Noticeable anti-aging effects
  • Improved skin quality and elasticity
  • Greater mental clarity and focus
  • More stable energy throughout the day

8 to 12 weeks:

  • Full systemic effect
  • Optimal cellular regeneration
  • Measurable biological rejuvenation
  • Maximum anti-aging benefits

Scientific studies show measurable increases in NAD+ within a few hours, while biological rejuvenation requires several months of regular supplementation.

Yes, NMN One combines very well and can even enhance other supplements:

Especially synergistic combinations:

  • Omega-3 fatty acids: improved cell membrane flexibility
  • Vitamin D3: optimized immune function and bone health
  • Magnesium: better ATP production and muscle function
  • Coenzyme Q10: enhanced mitochondrial energy production
  • B-complex vitamins: optimized energy metabolism

Already optimized in the formula:

  • Trans-resveratrol (sirtuin activator)
  • Quercetin phytosome (antioxidant)
  • BioPerine® (absorption enhancer)

Timing: Taking NMN One in the morning pairs well with evening supplements. If you use medications regularly, talk to your doctor.

Liposomal technology solves the biggest problem of conventional NMN supplements:

Problem with conventional NMN:

  • Is largely broken down in the digestive tract
  • Only 10 to 15% actually reaches the cells
  • Unreliable and weak effect
  • High doses needed for minimal effects

Solution through liposomal encapsulation:

  • NMN is enveloped with phospholipids
  • Direct fusion with cell membranes
  • Over 95% bioavailability (vs 10 to 15% conventional)
  • 10x higher NAD+ levels achieved

Scientific evidence:

  • Clinical studies confirm superior absorption
  • Measurably higher NAD+ increases
  • Faster and stronger anti-aging effect

This is the decisive difference between ineffective and highly effective NMN.

NMN One is particularly valuable from age 30 onward, as NAD+ levels steadily decline:

30 to 40 years (Prevention):

  • Maintain youthful cellular energy
  • Prevent age-related NAD+ losses
  • Optimize regenerative capacity
  • Dosage: 1 capsule daily

40 to 50 years (Optimization):

  • Active support for regeneration
  • Ease early signs of aging
  • Maintain cognitive performance
  • Dosage: 1 to 2 capsules daily

60+ years (Intensive regeneration):

  • NAD+ production reduced by 50 to 80%, with the greatest benefit
  • Noticeable improvement in vitality
  • Support for age-related concerns
  • Maximum anti-aging effects
  • Dosage: 2 capsules daily

Age-based dosing ensures optimal effects at every life stage according to individual NAD+ needs.

NMN One stands apart from other anti-aging products in fundamental ways:

Mechanism of action:

  • NMN One: Acts directly at the cellular level by restoring NAD+
  • Other products: Mostly address surface-level symptoms
  • Advantage: Targets the root causes of aging

Scientific foundation:

  • NMN One: Over 15 clinical human studies
  • Other products: Often only animal studies or lab tests
  • Advantage: Proven efficacy in humans

Quality & development:

  • NMN One: Physician developed, 99.8% pharmaceutical purity
  • Other products: Standard supplement-grade quality
  • Advantage: Medical precision instead of mass-market formulas

Bioavailability:

  • NMN One: Liposomal technology, 95% absorption
  • Other products: Conventional capsules, 10 to 20% absorption
  • Advantage: Measurable results instead of wasted potential

NMN One is thus the first holistic NAD+ booster for scientifically measurable cellular rejuvenation.

Authentic ratings and customer testimonials are available right on each product page. Simply scroll down or click the “Reviews” tab at the top to explore honest feedback and personal experiences with our products.

To preserve the quality, stability, and efficacy of Heilnatura dietary supplements over time, store them in a cool, dry place away from light. Direct sunlight, high humidity, and temperatures above 25 °C can affect sensitive ingredients. Keep products in a cabinet or drawer away from heat sources such as radiators or sunny windows. Bathrooms are generally not suitable because of higher humidity.

Heilnatura combines traditional natural medicine with modern quality criteria, which is how we ensure purity and safety:

  • In-house manufacturing in Europe
    We develop and produce our formulas ourselves to maintain full control over raw materials and processes.

  • Certified filling to HACCP & GMP / ISO 22000:2018
    Every production step follows strict hygiene and control requirements.

  • Contaminant-free storage
    Finished products are stored in special, contaminant-free containers.

  • Eco-friendly shipping
    Your order arrives in mineral-oil-free cartons. Sustainable and safe.

Our name “Heilnatura” stands for the connection between healing and nature. We draw on nature’s power, verified by state-of-the-art standards. For more about our values and approach, visit our philosophy page.

Our supplements are generally well tolerated and can also be taken alongside medications. If you use medicines on an ongoing basis, we recommend:

  • Doctor or pharmacist consultation: clarify potential interactions
  • Individual risk factors: discuss any pre-existing conditions or specific drugs in detail, for example anticoagulants or heart medications.

Our products are generally well tolerated because they are based on natural ingredients. However, people who are pregnant or nursing, as well as anyone with known allergies or medical conditions, should consult a doctor or qualified practitioner before use to rule out individual intolerances or contraindications. If you are unsure in general or have questions about tolerability, we also recommend seeking advice before taking.

We ship every order climate neutrally with DHL GoGreen. Within Germany your parcel usually arrives in 1 to 3 business days. Delivery to EU countries takes 3 to 10 business days depending on the destination.

The flat shipping rate is 4.90 € (DE) and is waived from 75 € order value.

For Austria, France, Belgium, and Italy the cost is 6.90 €. Other EU countries: 9.90 €. Switzerland and Liechtenstein: 15.90 €. The shipping fee is waived from 150 € order value.

All shipments are trackable, and orders placed on business days by 12 pm are usually handed over to DHL the same day.

Video
Mehr als nur Standard

Pharmazeutisches β-NMN – Reinheit auf höchstem Niveau

Für NMN One verwenden wir ausschließlich β-Nicotinamid-Mononukleotid in beispielloser Reinheit von 99,8% – gewonnen durch modernste biotechnologische Verfahren ohne chemische Lösungsmittel. Unser NMN wird ergänzt durch eine präzise Synergie-Matrix aus Trans-Resveratrol, Quercetin-Phytosom und BioPerine®, die synergistisch zusammenwirken und die Bioverfügbarkeit um das 10-fache steigern.

Liposomale Revolution – maximale Zellaufnahme

Die innovative liposomale Verkapselung umhüllt jeden Wirkstoff mit Phospholipiden und ermöglicht so eine direkte Zellmembran-Penetration. Während herkömmliche NMN-Produkte größtenteils ungenutzt ausgeschieden werden, erreicht NMN One eine Bioverfügbarkeit von über 95% – wissenschaftlich validiert und klinisch bestätigt.

Kapselhülle ohne Kompromisse

Für die Kapseln verwenden wir hochwertiges HPMC – ganz ohne Carrageen, PEG oder andere bedenkliche Zusatzstoffe. Die vegane Cellulose-Hülle löst sich schonend im Magen auf und gibt die wertvollen Inhaltsstoffe gezielt frei, ohne die empfindliche NAD+-Vorstufe zu beeinträchtigen.

Ärztlich entwickelt und wissenschaftlich fundiert

NMN One wurde von führenden Anti-Aging-Medizinern entwickelt und basiert auf über 15 klinischen Humanstudien. Jede Charge wird nach pharmazeutischen Standards geprüft und in lichtschützenden Braunglasflaschen verpackt – für maximale Wirkstoff-Stabilität und Potenz.

Produktdetails
Kapseln Pflanzliche Cellulose (HPMC), vegan
Premium-HPMC-Qualität: frei von den Zusatzstoffen Carrageen und PEG
Verpackung Vor Licht und Oxidation schützende Braunglasflasche (keine Weichmacher, BPA). Das beiliegende Silicagel dient dazu, Feuchtigkeit zu absorbieren und so die Frische sowie die Qualität des Produkts zu erhalten. Nicht zum Verzehr geeignet.
Entfernung des Etiketts zur Wiederverwendung der Gläser Zur Wiederverwendung der Glasflasche kann das Etikett durch 5 Minuten Einweichen in heißem Wasser leicht entfernt werden. Eventuelle Klebstoffreste lassen sich mit etwas Geschirrspülmittel abreiben.
Heilnatura

Our philosophy. 

At the heart of Heilnatura lies a simple yet profound belief: nature is the key to our health and wellbeing. Inspired by the ancient wisdom that nature is the greatest healer, we set out to harness this power in its purest form.

"Heilnatura"—a fusion of "healing" and "nature"—is not just our name; it reflects our commitment to uniting the art of naturopathy with modern science.

Learn more about Heilnatura

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