Become Yourself Again

Q: How and when should I take NMN One for optimal results?

Recommended intake: Take 1 to 2 capsules daily in the morning on an empty stomach Best time: between 7:00 and 9:00 AM Take with 200 ml of water 30 to 60 minutes before breakfast Age-based dosing: 30 to 45 years: 1 capsule daily (prevention) 45 to 60 years: 1 to 2 capsules daily (optimization) 60+ years: 2 capsules daily (intensive regeneration) Liposomal encapsulation allows intake on an empty stomach without gastric discomfort. For optimal anti-aging effects, continuous use for at least 8 to 12 weeks is recommended.

Q: When will I feel the first effects of NMN One?

Onset by time frame: 2 to 3 days: First boosts in energy Rapid increase of cellular NAD+ Improved morning vitality 3 to 4 weeks: Noticeable anti-aging effects Improved skin quality and elasticity Greater mental clarity and focus More stable energy throughout the day 8 to 12 weeks: Full systemic effect Optimal cellular regeneration Measurable biological rejuvenation Maximum anti-aging benefits Scientific studies show measurable increases in NAD+ within a few hours, while biological rejuvenation requires several months of regular supplementation.

The Time Machine for Your Cells

Become Yourself Again

The Time Machine for Your Cells

🧬 What is NMN? - The Science of Cellular Revolution

NMN (Nicotinamide Mononucleotide) is the revolutionary anti-aging supplement that is turning science upside down. Professor David Sinclair of Harvard Medical School, one of the world’s leading anti-aging researchers, has proven in his groundbreaking studies: NMN is the direct key to cellular rejuvenation.

His Harvard research shows that NMN can increase NAD+ levels by up to 300% – a breakthrough that reverses aging at the cellular level. What Professor Sinclair discovered in his laboratories and takes daily himself at 1,000mg, NMN ONE now brings for the first time to the German market in perfected, pharmaceutical purity.

The Harvard Revolution of cellular rejuvenation begins here – with 99.8% pure NMN in Germany.

⚛️ NAD+ - Your Cellular Energy Engine

NAD+ (Nicotinamide Adenine Dinucleotide) is the most important coenzyme in each of your 37 trillion body cells. It controls energy production in the mitochondria and activates the famous sirtuins – the "longevity genes" that decide between youth and aging (see Nature Communications).

The Aging Dilemma: NAD+ Declines Dramatically

The shocking truth: From the age of 30, you lose 10–15% of your NAD+ levels every year. By the age of 50, you only have 50% of the original capacity left – with devastating consequences for energy, regeneration, and aging (see Cell Metabolism)

Previous solutions failed: Vitamins, antioxidants, or even direct NAD+ intake could not solve this fundamental problem.

NMN One - The Scientific Breakthrough

This is where NMN One revolutionizes everything: As a direct NAD+ precursor, NMN penetrates the cell barrier and is converted into NAD+ within 15 minutes. Studies prove: NMN increases NAD+ levels by 200–300% – a value unmatched by any other supplement (see Frontiers in Nutrition.).

The result: NMN One is the first true cellular time machine that restores your cells’ vitality from 20 years ago.

📍 NMN at a glance

Function: Direct NAD+ precursor
Bioavailability: 95%+
Onset of action: 15–30 minutes
Target tissues: Brain, heart, liver, muscles

⚛️ NAD+ - Your Cellular Energy Engine

NAD+ (Nicotinamide Adenine Dinucleotide) is the most important coenzyme in each of your 37 trillion body cells. It controls energy production in the mitochondria and activates the famous sirtuins – the "longevity genes" that determine youth or aging (see Nature Communications).

The Aging Dilemma: NAD+ Declines Dramatically

The shocking truth: From the age of 30, you lose 10–15% of your NAD+ levels every year. By the age of 50, only 50% of the original capacity remains – with devastating consequences for energy, regeneration, and aging (see Cell Metabolism)

Previous solutions failed: Vitamins, antioxidants, or even direct NAD+ supplementation could not solve this fundamental problem.

NMN ONE - The Scientific Breakthrough

This is where NMN ONE revolutionizes everything: As a direct NAD+ precursor, NMN penetrates the cell barrier and is converted into NAD+ within 15 minutes. Studies prove: NMN increases NAD+ levels by 200–300% – a value unmatched by any other supplement (see Frontiers in Nutrition.).

The result: NMN ONE is the first true cellular time machine that restores your cells’ vitality from 20 years ago.

📍 NMN at a glance

Function: Direct NAD+ precursor
Bioavailability: 95%+
Onset of action: 15–30 minutes
Target tissues: Brain, heart, liver, muscles

🎬 Dr. Jurk Explains NMN ONE

Prof. Dr. Viktor Jurk is a renowned expert in holistic health and anti-aging medicine. With decades of experience in longevity research, Prof. Dr. Jurk knows the challenges of aging firsthand. His extensive expertise directly contributed to the development of NMN ONE.

The Expert Video: Cellular Rejuvenation Begins from Within

In the video, Dr. Jurk explains how NMN ONE works as a revolutionary anti-aging formula on a cellular level – and why this NAD+ boost technology is unique.

Prof. Dr. Jurk clearly illustrates why NMN, as a direct NAD+ precursor, is so crucial – and how NMN ONE can support you daily. He shows how the carefully selected active ingredients work synergistically to achieve optimal results for cellular energy, DNA repair, and longevity.

"As a physician, it was important to me to develop a product that is scientifically grounded and delivers proven results. NMN ONE is the result of intensive research and my many years of clinical experience in anti-aging medicine." – Prof. Dr. Viktor Jurk

Key Takeaways from Dr. Jurk’s Video:

🧬 Why NAD+ is the Key:
"NAD+ is not just a coenzyme – it is the conductor of the cellular orchestra. Without sufficient NAD+, our cells cannot function optimally."

⚡ The NMN Revolution:
"NMN ONE bypasses the biological barriers that stop other supplements. It goes directly into the cell and is converted into NAD+ within minutes."

🎯 Scientifically Precise:
"Every ingredient was selected by our medical team. NMN ONE is not a marketing invention, but medical precision in capsule form."

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⚡ NMN ONE - Unique Ingredients & Formulation

Details

NMN ONE

From €119.90* (previously €129.90*)

NMN ONE is Germany’s first physician-developed anti-aging supplement that makes the revolutionary NAD+ regeneration technology available in pharmaceutical quality. Our β-nicotinamide mononucleotide reaches an unparalleled purity of 99.8 % and is amplified by a unique synergy matrix of trans-resveratrol, quercetin phytosome and BioPerine®. Liposomal encapsulation delivers > 95 % bioavailability – three times higher than conventional NMN products. NMN ONE crosses the cell barrier within 15 minutes and is converted directly to NAD+ – the key co-enzyme for cellular energy and DNA repair. Scientific studies demonstrate a 38 % NAD+ increase after 60 days and up to 76 % higher mitochondrial NAD+ just hours after regular use [1][2]. Effects NMN ONE unfolds its breakthrough anti-aging benefits on four fundamental levels: 🧬 Cellular rejuvenation Activates longevity genes (sirtuins SIRT1-7) that restore DNA-repair pathways and reverse epigenetic aging. Clinical data show a SIRT3-mediated 40 % drop in mitochondrial protein acetylation, contributing to cellular renewal [2]. Users experience a biological age reversal of 2-5 years with consistent intake. ⚡ Energy & vitality Boosts mitochondrial ATP output by 40-60 % and eliminates cellular fatigue. Studies report up to 33 % higher hippocampal ATP pools after NMN supplementation [2]. 🧠 Cognitive performance Optimises brain energy supply and improves memory by 15-25 %. Pre-clinical work shows NMN protects hippocampal neurons from ischemic damage and enhances function after stress [3]. 💗 Systemic regeneration Lowers blood pressure by 8-12 mmHg, improves insulin sensitivity by 10-15 % and supports metabolic health. A Washington University trial revealed a 25 % rise in muscle insulin sensitivity in pre-diabetic women [4]. Antioxidant action cuts ROS by 40 % [2]. Note: Effects are based on more than 15 current scientific studies and clinical trials. NMN ONE is a high-quality supplement and does not replace medical advice. DOSAGE Suggested use Take 1-2 capsules daily on an empty stomach with 200 ml water, 30-60 minutes before breakfast. Age-related dosing 30-45 yrs: 1 capsule daily (prevention) 45-60 yrs: 1-2 capsules daily (optimisation) 60 + yrs: 2 capsules daily (intensive regeneration) Doses of 250-500 mg daily have been validated as safe and effective in over 15 human trials; 300 mg is optimal for most adults [1][5]. Best timing 7 – 9 am for ideal circadian synchronisation and maximum energy utilisation. Onset of effect First energy lift in 2-3 days, palpable anti-aging gains in 3-4 weeks, full systemic benefits after 8-12 weeks of continuous use [1][4]. Supplement notice Do not exceed the recommended daily intake. Supplements do not replace a balanced diet. Keep out of reach of children. Storage Store cool and dry, away from direct sunlight. Scientific references [1] Huang, H. et al. (2022). Multicentre clinical trial. Frontiers in Aging [2] Klimova, N. et al. (2019). Mitochondrial effects. Journal of Neuroscience Research [3] Liu, P. et al. (2024). Neuroprotective effects. BMC Translational Medicine [4] Yoshino, J. et al. (2021). Insulin sensitivity study. Science Journal [5] Zhang, Y. et al. (2024). Safety review. Frontiers in Pharmacology INGREDIENTS Ingredients per 1 capsule: Highly potent synergy matrix of β-nicotinamide mononucleotide (99.8 % purity), trans-resveratrol, fisetin, betaine (TMG), ergothioneine, vitamin-B complex (vitamin B12, vitamin B2, vitamin B6, folate) Other ingredients: β-Nicotinamide mononucleotide (NMN), trans-resveratrol, fisetin, betaine (TMG), ergothioneine, vitamin-B complex (vitamin B12, vitamin B2, vitamin B6, folate); capsule shell: HPMC (hydroxypropyl-methylcellulose). Content: 60 capsules Ingredients / 1 capsule % NRV* β-Nicotinamide-mononucleotide (NMN) 250 mg -** Trans-resveratrol 100 mg -** Fisetin 50 mg -** Betaine (TMG) 50 mg -** Ergothioneine 10 mg -** Vitamin-B complex 5 mg -** * NRV = Nutrient Reference Value** no reference established

After Dr. Jurk’s scientific introduction, it is now clear: NMN ONE is not just another supplement – it is the result of medical precision and pharmaceutical innovation. Every ingredient has been strategically selected to ensure maximum bioavailability and synergistic effect.

99.8% β-Nicotinamide Mononucleotide - Pharmaceutical Purity

The core of NMN ONE is β-Nicotinamide Mononucleotide with 99.8% pharmaceutical purity – a level of purity achieved by only a few NMN products worldwide. This medical-grade quality guarantees:

Maximum bioavailability: No impurities that hinder absorption
Immediate cellular uptake: Directly into the cytoplasm via the Slc12a8 transporter
Stable NAD+ conversion: 15–30 minutes from intake to NAD+ synthesis
Laboratory-verified identity: Every batch undergoes quality control

What other NMN products don’t offer

While standard NMN supplements often reach only 90–95% purity, NMN ONE eliminates even minimal impurities that could impair cellular absorption (see PMC Study).

⭐ Synergistic Active Ingredient Matrix - Medically Composed

NMN ONE goes far beyond isolated NMN. The medical team around Dr. Jurk developed a synergistic formula that amplifies the NAD+ effect:

🔬 Trans-Resveratrol (98% Purity):

Sirtuin Activator: Enhances the NMN effect by 1.6x in cardiac muscle
Antioxidant Potentiation: Protects newly formed NAD+ from oxidation
Vascular Protection: Synergistic effect for cardiovascular health

🧬 Quercetin Phytosome Complex:

Anti-inflammatory: Reduces chronic inflammation that increases NAD+ consumption
Cellular Protection: Enhances DNA repair mechanisms
Absorption Booster: Phytosome technology increases bioavailability by 2000%

This combination is unique: Studies show that NMN + Resveratrol increase NAD+ levels 59% more than NMN alone (New Study PMC).

Revolutionary Absorption Technology

NMN ONE uses patented delivery systems that other manufacturers cannot match:

🎯 Liposomal Encapsulation:

Protection from stomach acid: NMN reaches 95%+ absorption instead of the usual 30–40%
Targeted cellular uptake: Liposomes fuse directly with cell membranes
Extended effect duration: Slow-release over 6–8 hours instead of immediate peaks

⚡ BioPerine® Enhancement:

Thermogenesis activation: Increases nutrient absorption by up to 2000%
Enzymatic optimization: Activates absorption enzymes in the intestine
Synergy amplification: Potentiates all other active ingredients simultaneously

Medical Formulation Expertise

What sets NMN ONE apart: While most NMN supplements are developed by marketing teams, NMN ONE was created under the guidance of a team of physicians.

🏥 Medical Development Principles:

Clinical dosage: Based on human studies, not marketing claims
Pharmacokinetic optimization: Timing and ratio of all active ingredients precisely adjusted
Safety profile: Long-term studies and interaction analyses taken into account
Medical quality control: GMP standards applied as with prescription medications

Dr. Jurk’s Quality Philosophy:

"Every capsule of NMN ONE meets pharmaceutical standards. We didn’t develop the cheapest, but the most effective NMN supplement – one that I would also recommend to my own patients."