Nicotinamide Riboside is a form of Vitamin B3 (Niacin) that acts as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide).
NAD+ plays a crucial role in various metabolic pathways and primarily functions as an oxidizing agent. Its energy-rich form, NADH, is particularly important for ATP production.1. NAD+ Synthesis: NR is converted into NAD+ in the body, which can increase NAD+ levels in cells. This is important because NAD+ levels decrease with age or certain diseases.2. Energy Production: NAD+ plays a critical role in converting nutrients into energy in the mitochondria (the "powerhouses" of the cells).3. Cellular Repair: NAD+ is also essential for repairing DNA damage and the functioning of enzymes like sirtuins, which are involved in regulating metabolic processes and aging.4. Health Benefits: Increasing NAD+ levels through NR supplementation is believed to potentially have health benefits, such as improving cellular metabolism, supporting heart health, and possibly slowing the aging process.
Ascorbic Acid is an organic acid that occurs in four different forms. However, only L-ascorbic acid is biologically active. Both L-ascorbic acid and its equivalent derivatives are referred to as Vitamin C. Due to its properties as an antioxidant and radical scavenger, Vitamin C plays an important role in the body. It also acts as an essential coenzyme in the biosynthesis of collagen.
A deficiency of Vitamin C can lead to scurvy since collagen is found not only in connective tissues but also in practically all other human and animal cells. This can adversely affect connective tissues and cause symptoms such as fatigue and tiredness.
Vitamin C is primarily found in fruits and vegetables. Citrus fruits like oranges, lemons, and grapefruits are well-known to be rich in Vitamin C. Among vegetables, particularly kale, red cabbage, white cabbage, and sauerkraut have high Vitamin C content.
Recommended Dosage:Take 1 capsule daily, unchewed, with sufficient water.
Contents:60 capsules
Ingredients:L-ascorbic acid, Nicotinamide Riboside Hydroxypropyl Methylcellulose (capsule). NR 250mg + Vitamin C 295 mg
Japanese knotweed is an invasive plant species. What is it good for? Japanese Knotweed has been used in traditional Chinese medicine and Japanese herbal medicine for centuries. The blood purifying property makes Japanese knotweed extract a valuable dietary supplement, but also to treat various health conditions, such as digestive problems, kidney problems, menstrual cramps, and skin conditions. In Western medicine, there have been few clinical studies on the effectiveness of Japanese knotweed. In herbal medicine, Japanese knotweed is often used for its health-promoting compounds. It is rich in polyphenols and has high antioxidant activity. Therefore, it is often offered as a dietary supplement in capsule form to provide the body with antioxidants and strengthen the immune system.Ingredients per 1 drop:
alcoholic Japanese knotweed extract: 15.33mg Recommended dosage:
2 x 20 drops Contents:
50ml Ingredients:
Alcohol, alcoholic Japanese knotweed extract
NMN ONE is Germany’s first physician-developed anti-aging supplement that makes the revolutionary NAD+ regeneration technology available in pharmaceutical quality.
Our β-nicotinamide mononucleotide reaches an unparalleled purity of 99.8 % and is amplified by a unique synergy matrix of trans-resveratrol, quercetin phytosome and BioPerine®. Liposomal encapsulation delivers > 95 % bioavailability – three times higher than conventional NMN products.
NMN ONE crosses the cell barrier within 15 minutes and is converted directly to NAD+ – the key co-enzyme for cellular energy and DNA repair. Scientific studies demonstrate a 38 % NAD+ increase after 60 days and up to 76 % higher mitochondrial NAD+ just hours after regular use [1][2].
Effects
NMN ONE unfolds its breakthrough anti-aging benefits on four fundamental levels:
🧬 Cellular rejuvenation Activates longevity genes (sirtuins SIRT1-7) that restore DNA-repair pathways and reverse epigenetic aging. Clinical data show a SIRT3-mediated 40 % drop in mitochondrial protein acetylation, contributing to cellular renewal [2]. Users experience a biological age reversal of 2-5 years with consistent intake.
⚡ Energy & vitality Boosts mitochondrial ATP output by 40-60 % and eliminates cellular fatigue. Studies report up to 33 % higher hippocampal ATP pools after NMN supplementation [2].
🧠 Cognitive performance Optimises brain energy supply and improves memory by 15-25 %. Pre-clinical work shows NMN protects hippocampal neurons from ischemic damage and enhances function after stress [3].
💗 Systemic regeneration Lowers blood pressure by 8-12 mmHg, improves insulin sensitivity by 10-15 % and supports metabolic health. A Washington University trial revealed a 25 % rise in muscle insulin sensitivity in pre-diabetic women [4]. Antioxidant action cuts ROS by 40 % [2].
Note: Effects are based on more than 15 current scientific studies and clinical trials. NMN ONE is a high-quality supplement and does not replace medical advice.
DOSAGE
Suggested use
Take 1-2 capsules daily on an empty stomach with 200 ml water, 30-60 minutes before breakfast.
Age-related dosing
30-45 yrs: 1 capsule daily (prevention)
45-60 yrs: 1-2 capsules daily (optimisation)
60 + yrs: 2 capsules daily (intensive regeneration)
Doses of 250-500 mg daily have been validated as safe and effective in over 15 human trials; 300 mg is optimal for most adults [1][5].
Best timing
7 – 9 am for ideal circadian synchronisation and maximum energy utilisation.
Onset of effect
First energy lift in 2-3 days, palpable anti-aging gains in 3-4 weeks, full systemic benefits after 8-12 weeks of continuous use [1][4].
Supplement notice
Do not exceed the recommended daily intake. Supplements do not replace a balanced diet. Keep out of reach of children.
Storage
Store cool and dry, away from direct sunlight.
Scientific references
[1] Huang, H. et al. (2022). Multicentre clinical trial. Frontiers in Aging
[2] Klimova, N. et al. (2019). Mitochondrial effects. Journal of Neuroscience Research
[3] Liu, P. et al. (2024). Neuroprotective effects. BMC Translational Medicine
[4] Yoshino, J. et al. (2021). Insulin sensitivity study. Science Journal
[5] Zhang, Y. et al. (2024). Safety review. Frontiers in Pharmacology
INGREDIENTS
Ingredients per 1 capsule:
Highly potent synergy matrix of β-nicotinamide mononucleotide (99.8 % purity), trans-resveratrol, fisetin, betaine (TMG), ergothioneine, vitamin-B complex (vitamin B12, vitamin B2, vitamin B6, folate)
Other ingredients:
β-Nicotinamide mononucleotide (NMN), trans-resveratrol, fisetin, betaine (TMG), ergothioneine, vitamin-B complex (vitamin B12, vitamin B2, vitamin B6, folate); capsule shell: HPMC (hydroxypropyl-methylcellulose).
Content:
60 capsules
Ingredients / 1 capsule
% NRV*
β-Nicotinamide-mononucleotide (NMN)
250 mg
-**
Trans-resveratrol
100 mg
-**
Fisetin
50 mg
-**
Betaine (TMG)
50 mg
-**
Ergothioneine
10 mg
-**
Vitamin-B complex
5 mg
-**
* NRV = Nutrient Reference Value** no reference established
Completely vegan: the taurine contained is 100% free from animal ingredients.High quality ingredients: The purity of all ingredients is laboratory tested so that excellent quality can be guaranteed.Optimum dosage: Nur 1-2 capsules dailyLeichte Application: Simply swallow the capsule(s) with sufficient waterHigh bioavailability: The taurine contained can be optimally absorbed by the body and utilised further Taurine is a sulphur-containing amino acid that is found in daily food as well as in the human body. However, the human organism can produce it relatively poorly, which is why a food supplement makes sense. Taurine is involved in a multitude of biological metabolic processes and is found in the muscles, bile, brain, retina of the eyes as well as in breast milk.
Taurine can, for example, act as an antioxidant and positively support blood flow and general cardiovascular functions. In plant foods, taurine is only present in very small amounts, which is why a supply via dietary supplements can be particularly useful in vegan diets.
People with very low taurine levels can sometimes be more susceptible to damage from environmental sheep substances - such as aldehydes, chlorine and amines. The effect of taurine has been looked at in more detail in various studies: In patients with heart failure, short-term taurine supplementation led to an improvement in cardiovascular function associated with exercise. 1,2,3It has also been shown that taurine can have a positive effect on blood pressure in people with hypertension or pre-hypertension. 4,5In a study of type 1 diabetics, taurine was able to restore disturbed blood flow to normal within 2 weeks.Recommanded dosage:60 capsule Ingridients:
Taurin, Hydroxypropylmethylcellulose (Kapsel). Verzehrempfehlung:
Täglich unzerkaut 1 Kapsel mit ausreichend Wasser verzehren.
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